ACS Update – 2019 with James de Lemos

I caught up with Dr. James de Lemos from UT Southwestern at the 2019 American Heart Association meeting to discuss a number of updates in acute coronary syndromes. We cover a number of recent trials that are shaping how we think about ACS management from medications, stent deployment and the mechanism we might be overlooking.

Links to articles:

ISAR-REACT 5

TWILIGHT

POPular Genetics

COMPASS

Decompensated heart failure with Dr. Kittleson

In this episode I visit with Dr. Michelle Kittleson (@MKIttlesonMD) of Cedars-Sinai to discuss evaluation and management of patients admitted with acute decompensated heart failure. We review the etiologies for decompensation, what to do with beta-blockers or RAS inhibitors and how to setup the patient for a successful discharge.

Links to papers:

Effects of Beta-blocker Withdrawal Meta-Analysis

Early worsening renal function after initiation of ACE inhibitor, Testani Circulation Heart Failure 2011

DOSE Trial

Furosemide v Torsemide

PARADIGM-HF

DAPA-HF

ASDs and VSDs with Amber Khanna

In this episode I visit with Dr. Amber Khanna of the University of Colorado about some of the “simple” congenital heart defects. We discuss atrial septal defects (ASD) and ventricular septal defect (VSD). We review useful testing to diagnose and evaluate these defects and the indications for closure.

Links:

2018 ACC/AHA Guidelines for the Management of Adults with Congenital Heart Disease

Adult Congenital Heart Association